The effects of cannabis, cannabinoids, and their administration routes on pain control efficacy and safety: A systematic review and network meta-analysis

Posted on September 15, 2019

Abstract

Objectives: To determine the effects of cannabis, cannabinoids, and their administration routes on pain and adverse euphoria events.

Data sources: A systematic search was performed in PubMed, ScienceDirect, ClincalTrials.gov, Scopus, Cochrane Library, and Embase from inception until June 2017.

Study selection: Randomized controlled trials investigating the effects of cannabis or cannabinoids on pain reduction.

Data extraction: Two reviewers extracted and assessed the quality of studies by means of Cochrane risk of bias. Standardized mean difference (SMD) was calculated. Random-effects model was undertaken to pool the treatment effects.

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