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Posted on September 15, 2019
Objectives: To determine the effects of cannabis, cannabinoids, and their administration routes on pain and adverse euphoria events.
Data sources: A systematic search was performed in PubMed, ScienceDirect, ClincalTrials.gov, Scopus, Cochrane Library, and Embase from inception until June 2017.
Study selection: Randomized controlled trials investigating the effects of cannabis or cannabinoids on pain reduction.
Data extraction: Two reviewers extracted and assessed the quality of studies by means of Cochrane risk of bias. Standardized mean difference (SMD) was calculated. Random-effects model was undertaken to pool the treatment effects.